Imitrex and levothyroxine Interactions

Imitrex and levothyroxine Interactions

Imitrex and levothyroxine Interactions

In order for Synthroid to be effective, it should always be taken the same way every day. This is important because the amount of medicine you need is very precise. And even the way you take Synthroid can affect how much medicine your body is getting.

Monitor for cardiac arrhythmias during surgical procedures in patients with coronary artery disease receiving suppressive SYNTHROID therapy. Monitor patients receiving concomitant SYNTHROID and sympathomimetic agents for signs and symptoms of coronary insufficiency. The recommended daily dosage of SYNTHROID in pregnant patients is described in Table 3.

  • After another drug has been added to or removed from your regimen, you should report worsening of any disease symptoms or medication side effects to your doctor.
  • This is important as 32% of patients who think they are on SYNTHROID are actually not given this because substitutions are made at the pharmacy.
  • It is important to tell your doctor about all other medications you use, including vitamins and herbs.
  • No adverse effects on the breastfed infant have been reported and there is no information on the effects of levothyroxine on milk production.

5 Antidepressant Therapy

Using the levothyroxine dosage calculator is simple and intuitive. It will help you determine the drug’s right dose and give a hint of where to start and where to aim. Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson’s disease, serious infections, or prevention of nausea and vomiting. These medicines may interact with sumatriptan and cause a serious condition called serotonin syndrome.

How do I determine whether I have hypothyroidism?

It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. In adult patients with primary hypothyroidism, monitor serum TSH levels after an interval of 6 to 8 weeks after any change in dosage. In patients on a stable and appropriate replacement dosage, evaluate clinical and biochemical response every 6 to 12 months and whenever there is a change in the patient’s clinical status. The recommended starting daily dosage of SYNTHROID in pediatric patients with primary, secondary, or tertiary hypothyroidism is based on body weight and changes with age as described in Table 2.

Titrate the dosage (every 2 weeks) as needed based on serum TSH or free-T4 until the patient is euthyroid see Dosage and Administration (2.2). Myxedema coma is a life-threatening emergency characterized by poor circulation and hypometabolism and may result in unpredictable absorption of levothyroxine sodium from the gastrointestinal tract. Use of oral thyroid hormone drug products is not recommended to treat myxedema coma.

Warnings

Avoid driving or hazardous activity until you know how this medicine will affect you. You may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects. Biochemical assessment incorporated measurement of serum TSH, T3, and T4. TSH lower limit of quantification was 0.2 mIU/L and upper limit of normal was 5.6 mIU/L, as indicated by the shaded area. Some key points that I discuss with the patients during appointments are, one, is that this is an open conversation.

  • Therefore, a decrease in the dose of anticoagulant may be warranted with correction of the hypothyroid state or when the SYNTHROID dose is increased.
  • Measure and evaluate unbound (free) hormone and/or determine the free-T4 index (FT4I) in this circumstance.
  • Closely monitor blood pressure and heart rate in these patients.
  • If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications.

Call your doctor if your symptoms do not improve, or if you have more than 4 headaches in one month (30 days). Use the drop-down menu below to select your state and see the specific language required to prevent generic substitution. When prescribing SYNTHROID, protecting your script can ensure your patients receive SYNTHROID every time they refill their prescription. That’s because substitutions can be made at the pharmacy if the prescription is not properly protected with the Dispense as Written (DAW) state-specific language.

Published studies report that levothyroxine is present in human milk following the administration of oral levothyroxine. No adverse effects on the breastfed infant have been reported and there is no information on the effects of levothyroxine on milk production. Adequate levothyroxine treatment during lactation may normalize milk production in hypothyroid lactating mothers with low milk supply. Addition of levothyroxine therapy in patients with diabetes mellitus may worsen glycemic control and result in increased antidiabetic agent or insulin requirements. Carefully monitor glycemic control after starting, changing, or discontinuing SYNTHROID see Drug Interactions (7.2).

Carefully monitor glycemic control, especially when thyroid therapy is started, changed, or discontinued see Warnings and Precautions (5.5). Thyroid hormone increases metabolic clearance of glucocorticoids. Initiation of thyroid hormone therapy prior to initiating glucocorticoid therapy may precipitate an acute adrenal crisis in synthroid bipolar patients with adrenal insufficiency.

Concurrent use of tyrosine-kinase inhibitors such as imatinib may cause hypothyroidism. Monitor serum free-T4 levels and maintain in the upper half of the normal range in these patients. Do not administer in foods that decrease absorption of SYNTHROID, such as soybean-based infant formula see Drug Interactions (7.9). Whether treated or not, subclinical hypothyroidism is a yellow flag that should put a patient on a ‘regular thyroid laboratory tests’ list. Remember to test TSH not earlier than 6-8 weeks after treatment initiation or levothyroxine dosage change. The pituitary gland controls the thyroid gland by the TSH — thyroid-stimulating hormone, which stimulates the thyroid to produce hormones.

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